Recent Posts

GARNet2016 CRISPR/Cas workshop presentation

Slides from the recent CRISPR/Cas workshop held at the GARNet2016 meeting are now available to download. Organized by Vladimir Nekrasov and Amanda Hopes (The Sainsbury Laboratory/University of East Anglia, UK), the workshop title was, "Introduction to CRISPR-Cas, troubleshooting target design…

Did a Swedish researcher eat the first CRISPR meal ever served?

From Science, By Jon Cohen Sep. 7, 2016 http://www.sciencemag.org/news/2016/09/did-swedish-researcher-eat-first-crispr-meal-ever-served In what Swedish plant scientist Stefan Jansson declares “maybe” a historic event, he cultivated, grew, and ate a plant that had its genome edited with CRISPR-Cas9.…

Transcript, protein and metabolite dynamics in CAM-plant Agave ($)

Crassulacean acid metabolism (CAM) is a specialized form of photosynthesis that greatly increases water-use efficiency by taking up CO2 through stomata that are open at night (when evapotranspiration is low). Engineering plants that can switch to CAM during periods of drought is a key goal towards…

Molecular basis for plant growth responses in shade and under competition for light ($)

The wavelenghts of light perceived by a plant are information-rich, and plants integrate information from photoreceptors tuned to different wavelenghts to optimize their growth and development. Because plants absorb red light but not far-red light, a low ratio of red to far-red light indicates vegetative…

Light suppresses ethylene response by direct interaction between phyB and EIN3

A seedling in the dark produces ethylene, which in a dicot such as Arabidopsis leads to apical hook formation that protects the cotyledons from damage as the seedling pushes through the soil. The emergence of the seedling into the soil causes a rapid transition to photomorphogenesis and a suppression…

Auxin production in the endosperm drives seed coat development in Arabidopsis

Seed vitality is critical for plants’ evolutionary survival and food production by economic crops such as rice, wheat, etc. Seed formation is preceded by well-coordinated events involving mainly fertilization, endosperm and seed coat formation in chronological order. How is the signal relayed from…

Hormone-mediated inflorescence patterning in barley ($)

Youssef et al. investigate how the vsr2 mutant affects inflorescence (spike) development in barley. In the two-row variety, at each node there are two sterile spikelets and a single grain forms. In the six-row variety, each of the spikelets is fertile and three grains form at each node. The vsr2 mutation…

Metabolic Signaling Regulates Alternative Splicing during Photomorphogenesis

IN BRIEF by Kathleen L. Farquharson kfarquharson@aspb.org Alternative splicing (AS) regulates gene expression and greatly expands the coding capacity of complex genomes. By regulating which elements of an mRNA transcript are removed or retained, AS produces multiple transcripts from a single gene. Some…

RNA Degradome Studies Give Insights into Ribosome Dynamics

IN BRIEF by Gregory Bertoni gbertoni@aspb.org RNA metabolism is key to a number of crucial processes in the cell, including transcription, RNA splicing, translation, and gene regulation. For efficient translation, mature mRNAs must have a 7-methylguanosine cap on the 5′ end to help recruit the translation…