Tag: Genomics

By C. Robin Buell Unlike molecular biology techniques that are routinely used in individual investigator labs, the high cost of infrastructure historically has resulted in genome sequencing being performed at genome centers in which quality control and quality assessments are a mainstay, and it is…

Polyploidy can result either through genome doubling followed by intraspecific crosses, or when two genomes from independent species hybridize, leading to autopolyploidy, or allopolyploidy, respectively. Polyploidy is an important evolutionary tool; the resultant redundancy from the duplication of genes…

Every now and then a technology arrives on the scene that suddenly makes everything easier. When I was a student, PCR was developed. More recently, CRISPR/Cas9 applications were developed, and now the hot tool is nanopore flow cell sequencing. The crucial advancement in this method is that rather than…

Germplasm collections are invaluable resources for plant science and the elemental content of the seeds is a strong indication of the plant’s response to its specific environment. In this study, Ziegler et al. have selected 1,653 soybean accessions from the USDA Soybean Germplasm Collection and seeds…

In maize, it has long been known that the crossing of two inbred lines can produce a hybrid offspring with higher yield than the parents. Baldauf and collaborators have studied the gene expression of 6 hybrid lines coming from 7 distantly related inbred lines. One line, B73, was chosen as the common…

In order to use wild rice relatives for future crop improvement, the differences and similarities between wild and domesticated genomes need to be understood. Stein and colleagues sequenced the genomes of two domesticated varieties and seven wild species, unraveling 15 million years of evolutionary history…

Nat. Genet. Silencing of transposable elements (TEs) is mediated epigenetically by DNA methylation, relying partially on RNA-directed DNA methylation (RdDM). RdDM-induced DNA methylation undergoes a global reprogramming in the male germline, allowing expression of imprinted genes regulating fertility…

BioRxiv. Transcriptomic changes at the cellular level are of key importance in specialized cellular types. Therefore, transcriptome analysis at a cell-specific resolution is a powerful tool to learn about biological processes. This analysis is however limited by technological boundaries of microdissection…