Overcoming Algal Vitamin B12 Auxotrophy by Experimental Evolution
Vitamin B12 (B12) is produced only by prokaryotes (Fang et al., 2017), but is also widely required among eukaryotes as an enzymatic cofactor. In the green lineage, the only B12-dependent enzyme is methionine synthase. Several green algae can synthesize methionine only thanks to B12 provided by mutualistic prokaryotes (Croft et al., 2005, Grant et al., […]
