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UMP pyrophosphorylase-a moonlighting protein with essential functions in chloroplast development and photosynthesis establishment

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Pyrimidine nucleotides (e.g., dCTP, dTTP, UTP, and CTP) are essential building blocks for DNA and RNA synthesis in all organisms. In plants, sucrose and cell wall polymer synthesis depend on pyrimidine nucleotide-derived substrates, such as UDP-glucose, and important classes of membrane lipids are made…