Recent Posts

GARNet2016 CRISPR/Cas workshop presentation

Slides from the recent CRISPR/Cas workshop held at the GARNet2016 meeting are now available to download. Organized by Vladimir Nekrasov and Amanda Hopes (The Sainsbury Laboratory/University of East Anglia, UK), the workshop title was, "Introduction to CRISPR-Cas, troubleshooting target design…

Two-cell metabolism in multicellular cyanobacteria ($)

Nitrogen-fixing cyanobacteria such as Anabaena sp. PCC 7120 have the challenge of supporting nitrogenase, an enzyme that is highly sensitive to oxygen, and simultaneously photosynthesis, an oxygen-producing set of reactions. They accomplish this by segregating these reactions into two cells, heterocysts…

RNA Degradome Studies Give Insights into Ribosome Dynamics

IN BRIEF by Gregory Bertoni gbertoni@aspb.org RNA metabolism is key to a number of crucial processes in the cell, including transcription, RNA splicing, translation, and gene regulation. For efficient translation, mature mRNAs must have a 7-methylguanosine cap on the 5′ end to help recruit the translation…

Ticket to Ride: tRNA-Related Sequences and Systemic Movement of mRNAs

IN BRIEF by Jennifer Mach jmach@aspb.org Movement of macromolecules through the plant phloem provides a mechanism for long-distance signaling that plants use in development, disease resistance, and other adaptive responses (reviewed in Spiegelman et al., 2013). For example, full-length RNAs, such…