Tag: Gene Regulation

Wax covering the outer surface of the shoot (epicuticular wax) is crucial in the ability of the plant to conserve water. Wang et al. identified a drought hypersensitive plant that overexpresses an E3 ubiquitin ligase which they named DROUGHT HYPERSENSITIVE. In these overexpression plants, there was a…

The Mediator complex is a transcriptional co-regulator that is conserved across kingdoms. Several subunits have been identified through genetic approaches in Arabidopsis. Recessive loss-of-function mutants of MED5 subunits cause phenylpropanoid overaccumulation, but ef4-3, a semi-dominant mutation of…

Flower color pattern is a major trait influencing pollinator attraction, but underlying regulatory mechanisms are still poorly understood. Using co-existing Snapdragon subspecies displaying different flower pigmentation motifs, Bradley et al. investigated the molecular basis of flower color patterning.…

The C-terminal domain (CTD) of RNA polymerase II (Pol II) extends from the catalytic core and consists of repeats of a seven-amino acid motif. The CTD functions in the regulation of Pol II function and is subject to just about every protein modification you can think of, including methylation, acetylation,…

By Thanin Chantarachot and Julia Bailey-Serres The export of an mRNA from the nucleus to the cytoplasm begins an odyssey of dynamic regulation that determines the location, longevity and use of the transcript in the production of polypeptides by ribosomes in plant cells. Recent leveraging of mutants,…

Wheat (Triticum aestivum) yields can be severely reduced by the obligate biotrophic pathogen Puccinia striiformis f. sp. tritici (Pst).  Currently, approaches to manage this disease rely on cultivar resistance coupled with fungicide application. However, driven by a greater need for wheat production,…

What gives stem cells their plasticity and why are differentiated cells so specialized? Sijacic et al. approach this question by analyzing transcription factor (TF) accessibility to chromatin. Nuclei were isolated from shoot apical meristem (SAM) pluripotent stem cells and fully-differentiated mesophyll…

Previous studies have shown that some genes use multiple promoters, but the extent to which this occurs has not been fully resolved. Ushijima et al. showed widespread phytochrome-mediated differential promoter use in response to light. They identified more than 2000 genes with light-dependent alternative…