Recent Posts

Size no longer matters: Cloning algal genes just became easier

Emrich-Mills and Yates et al. develop a method for the large-scale cloning of Chlamydomonas genes without sequence length or complexity limits. The Plant Cell (2021) https://doi.org/10.1093/plcell/koab024  By Tom Z. Emrich-Mills, Gary Yates, and Luke C.M. Mackinder  Background: Chlamydomonas…

Chlamydomonas genomics: no longer going it alone

By Rory J. Craig, Institute of Evolutionary Biology, University of Edinburgh  Craig and colleagues report the sequencing and gene annotations of close and more distant relative of the unicellular alga Chlamydomonas reinhardtii, an emerging model organism for plant biology.  Background: The single-cell…

Chlamydomonas keeps the rhythm going

By Patrice Salomé, Department of Chemistry and Biochemistry, UCLA, Los Angeles, CA  Salomé and Merchant analyze hundreds of RNA-seq samples in the single-cell green alga and discover vast co-expression potential and surprising residual synchronized expression across samples derived from cultures…

Systematic characterization of gene function in a photosynthetic organism (bioRxiv)

Vilarrasa-Blasi and coworkers described their impressive work on a huge barcoded Chlamydomonas collection, in which they screened almost 60,000 insertion mutants grown under a wide range of environmental and chemical stress conditions. The authors assessed genotype-phenotype specificity for almost…

How to go quiet: CHT7 regulates cell cycle exit in Chlamydomonas (Plant Cell)

Many microbes enter a state of low metabolic activity, called quiescence, when the conditions for growth and division become unfavorable. The transition from active proliferation to quiescence involves a comprehensive restructuring of cellular metabolism, accumulation of storage compounds, and an orderly…