Recent Posts

Autophagy: Both Friend and Foe in Pseudomonas Infection

Eukaryotes use two major systems for getting rid of unwanted proteins: the ubiquitin proteasome system and autophagy. The proteasome degrades ubiquitinated proteins. Autophagosomal vesicles encapsulate cellular waste and either deliver it to the vacuole or fuse with a lysosome. Animal cells use autophagy…

Trust but Verify: A Lesson in Technology Limitations and Error Propagation

By C. Robin Buell Unlike molecular biology techniques that are routinely used in individual investigator labs, the high cost of infrastructure historically has resulted in genome sequencing being performed at genome centers in which quality control and quality assessments are a mainstay, and it is…

Transcriptomics of deepwater rice (Plant Physiol)

For most plants, becoming submerged under water can be lethal due to a restriction in gas exchange. One strategy for submergence tolerance is called an escape strategy, such as that employed by deepwater rice; the plant elongates rapidly to raise its leaves above the water level. Minami et al. used transcriptomics…

Crystal structure and pH dependency of peptidase & ligase activity in Arabidopsis legumain (Plant Cell)

Legumains are proteins identified first from legumes that have subsequently been identified in other organisms. They are also described as asparaginyl endopeptidases (AEPs) and vacuolar cysteine proteases or vacuolar processing enzymes. Enzymatically, legumains can express peptidase and peptide ligase…

A family of small, cyclic peptides buried in preproalbumin since the Eocene epoch (Plant Direct)

Small cyclic peptides are produced in many organisms; some are produced by ribosomes and others not. Fisher et al. explore a class of small cyclic peptides known as orbitides, which have been identified in plants of Asteroideae subfamily of the plant family Asteraceae. The fact that these are abundant…

Why and how plants make puzzle cells (eLIFE)

In proliferating tissues, plant cells start small and then expand to up to 100 times their original size. Sapala, Runions and collaborators studied the relationship between mechanical stress and shape to see if mechanical stress could affect the shape of epidermal cells. Simulations were run to see the…

The subgenomes of polyploid plants evolve at different rates (Plant Cell)

Polyploidy can result either through genome doubling followed by intraspecific crosses, or when two genomes from independent species hybridize, leading to autopolyploidy, or allopolyploidy, respectively. Polyploidy is an important evolutionary tool; the resultant redundancy from the duplication of genes…

Impact of genetically engineered maize on agronomic, environmental and toxicological traits (Sci. Rep.)

The question of the relative risks and benefits of genetically engineered (GE) maize is still in the middle of a heated debate, despite the widespread cultivation of GE crops (12% of the global crop-land) and long standing commercialization (since 1996).  Pellegrino et al. report a meta-analysis of…

Gibberellin DELLA signaling targets the retromer complex to redirect protein trafficking to the plasma membrane (PNAS)

Gibberellins including gibberellic acid (GA) are plant hormones required for growth and development. GA has been reported to regulate tropic responses by modulating plasma membrane localization of PIN auxin transporters. In this study, Salanenka et al. focused on the mechanism of GA-mediated protein…