Base-editing-mediated artificial evolution of OsALS1 in planta to develop novel herbicide-tolerant rice germplasms (Mol. Plant)
The trait of herbicide tolerance allows farmers to use chemical means to eliminate weed competitors. Acetolactate synthase (ALS) is an enzyme targeted by more than 50 different herbicides. In order to generate novel herbicide tolerance traits, Kuang et al. used a base-editing artificial evolution approach, by targeting nucleotide-modifying enzymes (cytosine deaminase and adenosine deaminase) to […]
