Recent Posts

Assembling a Nanomolecular Power Station

Zhang et al. investigate the assembly of a molecular motor that produces cellular ATP in chloroplasts https://doi.org/10.1105/tpc.18.00075. By Lin Zhang, Lianwei Peng and Jean-David Rochaix Background: The F-type ATP synthase produces nearly all of the cellular ATP, the universal energy currency…

Review: New insights into the plant epitranscriptome ($) (J. Exp. Bot.)

Just like the epigenome is the collection of epigenetic marks on DNA, the epitranscriptome is the collection of epigenetic marks on mRNA. Vandivier and Gregory review our current understanding of the epitranscriptome, with a focus on N6-methyladenosine (m6A) and 5-methylcytosine (m5C), and their various…

A single transcription factor promotes both yield and immunity in rice ($) (Science)

Plants regularly prioritize either growth or defense, leading to reduced growth rate when the plant is under attack. Wang et al. have identified a simple switch  in rice that demonstrates this principle beautifully. The Ideal Plant Architecture 1 (IPA1) transcription factor is involved in controlling…

Metabolic Fate of Modified Nucleotides after RNA Turnover, an Overlooked Issue in RNA Modification

Chen et al. reveal a multilayer molecular protection system functioning in Arabidopsis and human cells https://doi.org/10.1105/tpc.18.00236 By Mingjia Chen and Claus-Peter Witte Background: RNA possesses over 100 distinct posttranscriptional modifications in eukaryotic species. N6-methyladenosine…

Evolution of Gene Regulation During Domestication

Liu, et al. examine how wound response and its control mechanism differs between domesticated and wild tomato. Plant Cell https://doi.org/10.1105/tpc.18.00194. By Ming-Jung Liu and Shin-­Han Shiu Background: Two related species accumulate differences between each other over time. If one of the…

Dynamic Alternative Splicing Response to Cold

Calixto et al. demonstrate a rapid wave of alternative splicing as temperatures drop. The Plant Cell (2018) https://doi.org/10.1105/tpc.18.00177. By Cristiane Calixto and John Brown Background: Alternative splicing (AS) allows a single gene to produce more than one transcript, which can affect…

Tectonic Movements Across the Tomato Genome

Corem et al. demonstrate a switch in DNA methylation patterns across the tomato genome. The Plant Cell (2018). https://doi.org/10.1105/tpc.18.00167. By Shira Corem, Tzahi Arazi and Nicolas Bouché Background: Crop genomes are covered by transposons, which are DNA sequences that can jump from one…

Genome-Wide Assessment of Alternative Splicing in Maize

Chen et al. higlight the importance of AS in diversifying gene function and regulating phenotypic variation. The Plant Cell https://doi.org/10.1105/tpc.18.00109 Background: Alternative splicing (AS) of precursor mRNAs is an essential regulatory mechanism that greatly enhances transcriptome and proteome…

Heterochromatin keeps RNA-directed DNA methylation in place?

Fu et al. demonstrate a requirement for the heterochromatin factors CMT and DDM1 in RNA-directed DNA methylation in maize. Plant Cell https://doi.org/10.1105/tpc.18.00053 By Fang-fang Fu and Jonathan I. Gent
 Background: DNA methylation is a chemical modification of DNA consisting of addition…