Recent Posts

Metabolic Fate of Modified Nucleotides after RNA Turnover, an Overlooked Issue in RNA Modification

Chen et al. reveal a multilayer molecular protection system functioning in Arabidopsis and human cells https://doi.org/10.1105/tpc.18.00236 By Mingjia Chen and Claus-Peter Witte Background: RNA possesses over 100 distinct posttranscriptional modifications in eukaryotic species. N6-methyladenosine…

Evolution of Gene Regulation During Domestication

Liu, et al. examine how wound response and its control mechanism differs between domesticated and wild tomato. Plant Cell https://doi.org/10.1105/tpc.18.00194. By Ming-Jung Liu and Shin-­Han Shiu Background: Two related species accumulate differences between each other over time. If one of the…

Dynamic Alternative Splicing Response to Cold

Calixto et al. demonstrate a rapid wave of alternative splicing as temperatures drop. The Plant Cell (2018) https://doi.org/10.1105/tpc.18.00177. By Cristiane Calixto and John Brown Background: Alternative splicing (AS) allows a single gene to produce more than one transcript, which can affect…

Tectonic Movements Across the Tomato Genome

Corem et al. demonstrate a switch in DNA methylation patterns across the tomato genome. The Plant Cell (2018). https://doi.org/10.1105/tpc.18.00167. By Shira Corem, Tzahi Arazi and Nicolas Bouché Background: Crop genomes are covered by transposons, which are DNA sequences that can jump from one…

Genome-Wide Assessment of Alternative Splicing in Maize

Chen et al. higlight the importance of AS in diversifying gene function and regulating phenotypic variation. The Plant Cell https://doi.org/10.1105/tpc.18.00109 Background: Alternative splicing (AS) of precursor mRNAs is an essential regulatory mechanism that greatly enhances transcriptome and proteome…

Heterochromatin keeps RNA-directed DNA methylation in place?

Fu et al. demonstrate a requirement for the heterochromatin factors CMT and DDM1 in RNA-directed DNA methylation in maize. Plant Cell https://doi.org/10.1105/tpc.18.00053 By Fang-fang Fu and Jonathan I. Gent
 Background: DNA methylation is a chemical modification of DNA consisting of addition…

Function of m6A in Arabidopsis

Wei et al. Study m6A binding protein ECT2 in Arabidopsis. The Plant Cell (2018). https://doi.org/10.1105/tpc.17.00934 By Lian-Huan Wei Background: N6-methyladenosine (m6A) is the most abundant chemical modification of eukaryotic messenger RNA (mRNA). The regulation of m6A modification plays important…

Decoding RNA Methylation Regulates Trichome Branching

Scutenaire et al. show that a YTH domain protein acts as a reader of m6A mRNA modifications, thereby playing crucial roles in trichome branching, likely by acting on mRNAs in the cytosol. Plant Cell (2018). https://doi.org/10.1105/tpc.17.00854 By J. Scutenaire and C. Bousquet-Antonelli Background:…

Rice Panicle Morphogenesis: Intercommunication Between Grain Number and Size

Guo et al. investigate the trade-off between seed number and seed size of rice. Plant Cell (2018) https://doi.org/10.1105/tpc.17.00959. By Tao Guo, Ke Chen, Nai-Qian Dong, Chuan-Lin Shi, Wang-Wei Ye, Ji-Ping Gao, Jun-Xiang Shan, Hong-Xuan Lin Background: Rice is one of the main staple cereal crops…