Biosynthesis of the nitrogenase active-site cofactor precursor NifB-co in Saccharomyces cerevisiae (PNAS)
Nitrogenases are large, multisubunit enzymes that require complex metal cofactors. They are the only enzymes capable of fixing N2 into usable form, and are only produced by some archaea and bacteria; “nitrogen-fixing” legumes actually depend on the presence of their bacterial symbionts for this function. Because applying nitrogenous fertilizers to crops is environmentally costly, many […]
