Update: Nuclear Cap-Binding Complex in Abiotic Stress Responses
By Agata Daszkowska-Golec The nuclear cap-binding 16 complex (nCBC) in higher eukaryotes specifically binds to the monomethylated (7-methylguanosine (m717 GpppN)) cap structure at the 5¢ end of freshly transcribed mRNA. In addition to protecting mRNAs from degradation by exonucleases, the nCBC functions in transcription, polyadenylation, splicing, miRNA biogenesis and the nuclear export of capped RNAs. […]