Mechanistic basis for the activation of membrane receptor kinases by SERK-family coreceptors (PNAS)
LRR-RKs (Leucine-Rich Repeat Receptor Kinases) are membrane-spanning receptor molecules that recognize a diverse array of signaling ligands. SERKs (SOMATIC EMBRYOGENESIS RECEPTOR KINASEs) are co-receptors that are required for signal processing. Like LRR-RKs, SERKs span the membrane, with an intracellular kinase domain and an external LRR ectodomain, but the SERK ectodomain is smaller than that of […]