Mediator complex subunits in the regulation of phenylpropanoid biosynthesis ($)
The Mediator complex is a transcriptional co-regulator that is conserved across kingdoms. Several subunits have been identified through genetic approaches in Arabidopsis. Recessive loss-of-function mutants of MED5 subunits cause phenylpropanoid overaccumulation, but ef4-3, a semi-dominant mutation of a MED5 subunit leads to dwarfism and decreased phenylpropanoid accumulation. Other studies suggest that MED5 may function as […]