Entries by Emily Larson

Plant Tomosyn is a negative regulator of SNARE-mediated secretion in pollen

Emily R Larson, emily.larson@bristol.ac.uk Vesicle transport is one of those molecular processes that is easy to take for granted. From cell expansion and polarised growth to protein regulation and signalling, vesicle trafficking plays its unsung part. We tend to believe that we know a lot about this process and in truth, we do. Much work […]

Timing is Everything: Tandem Fluorescent Timers Expand Our Understanding of Protein Longevity

Signaling within and between cells is fast and dynamic. Such signals can involve the transport of charged ions that change membrane polarity or intercellular gradients, protein de/phosphorylation, protein interactions, and phytohormones, among others. The change in protein distribution in response to these signals is hard to measure, particularly in real time, which limits our understanding […]

Two pathways for trafficking the borate receptor BOR1

Polar localization of plasma membrane proteins is an important way cells regulate signaling pathways, transport across membranes, and growth. Polarization has obvious cellular effects, but localization of membrane components also contributes significantly to processes such as tip growth in root hairs and pollen tubes, phytohormone signaling, and directional micronutrient transport (Grunewald and Friml, 2010; Leitner […]

A Method to the Madness: Using Persistent Homology to Measure Plant Morphology

As the study of plant variation and characterization moves from measurements of largely organismal-level polymorphisms to those of cellular- and molecular-level traits, the need for morphological measuring tools that incorporate complex trait information is clear. While quantitative methodologies have improved, current methods rely on the researcher evaluating what morphological metrics to measure, and this results […]