Wounding triggers callus formation via dynamic hormonal and transcriptional changes

Plants are known for their ability to regenerate tissues following wounding. Wound repair requires the induction of cell proliferation, leading to the formation of undifferentiated callus at the wound site, followed by cell differentiation. Ikeuchi et al. explored transcriptional changes following wounding damage to the hypocotyl, and through mutant analysis and measurement of hormones evaluated the contributions of hormones to wound repair. The authors identified a key role for cytokinins and a set of wound-induced transcription factors in callus formation. Plant Physiol. 10.1104/pp.17.01035