Recent Posts

Colour bio-factories: Towards scale-up production of anthocyanins in plant cell cultures (Metabolic Engineering)

Anthocyanins are common plant pigments that provide dietary benefits, leading to an increase in their use as food coloring agents. However, purifying anthocyanins from current plant sources (such as waste grape skins, red cabbage, and berries) is expensive and creates a variable product. Modifying biosynthetic…

From Golden Rice to aSTARice: Bioengineering astaxanthin biosynthesis in rice endosperm (Molecular Plant)

Zu et al., have successfully harnessed the power of synthetic biology to increase the nutritional content of rice by overexpressing only four synthetic genes in rice endosperm. Here, the authors have created a colorful gradient of carotenoid-enriched rice by expressing two, three, and then four genes…

A synthetic oxygen sensing device for plants

Plants can die from a lack of oxygen (hypoxia), which contributes to the devastating losses caused by flooding. Iacopino et al. set out to develop a more specific method for detecting oxygen levels in plants, based on the mammalian Hypoxia Inducible transcription Factor HIF.  HIF is hydroxylated by…

Plant Synthetic Biology 101

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Plant Synthetic Biology 101 Recorded November 2018 About This Webinar Synthetic biology is an emerging discipline that seeks to apply engineering principles to biology. But what does this actually mean? How does it differ from what has come before? And what challenges are presented by pursuing…

Update: Engineering of metabolic pathways using synthetic enzyme complexes

By Nicholas Smirnoff, University of Exeter. This article is part of the forthcoming Synthetic Biology focus issue. Plants provide a source of enzymes for metabolic engineering to produce valuable or useful products in micro-organisms or can themselves be engineered (Andre et al., 2016; Vickery et…

Review: Changing form and function through carotenoids and synthetic biology (Plant Physiol)

Plants produce hundreds of carotenoids with functions ranging from photoprotection to signalling, and with important roles in human health as well. Wurtzel describes opportunities arising from applying the tools of synthetic biology to carotenoids. The regulation of carotenoid biosynthesis is complex,…

A rationally designed JAZ subtype-selective agonist of jasmonate perception (Nature Comms.)

Many plant hormones have pleiotropic effects, switching on and off multiple, seemingly unrelated processes. As an example, jasmonates both turn on herbivore defense responses and suppress growth. Takaoka et al. have elegantly separated these, by developing a jasmonate mimic that only activates defences.…

Perspective: The multiplanetary future of plant synthetic biology

The exploration of space is one of the most inspiring areas of scientific research and a major driver of technological innovation. One of the major factors limiting human expansion trough space is the immensely high cost of resupplying resources from Earth. Mars is the closest neighbor to Earth and although…

Paint the tobacco red: Anthocyanin production in tobacco cells lines

Anthocyanins are common plant pigments that provide dietary benefits, causing an increase in their use as a food coloring agents. However, purifying anthocyanins from current plant sources (such as waste grape skins, red cabbage and berries) is expensive and creates a variable product. Modifying biosynthetic…