Tag: Research Methods and Tools

Cells are as small as life gets, but can be much larger than they appear if given room for expansion. This is possible with expansion microscopy, a technique that enables three dimensional cell imaging by physically expanding cellular components for visualization. Although expansion microscopy has been…

How can we precisely image plant tissues in super-resolution when approaching the optical limits of conventional microscopes? One solution lies in expansion microscopy, a technique that embeds tissue samples in an expandable hydrogel that proportionally increases the distances between structures, allowing…

For living organisms, proper control of element location is just as important as the control of enzyme location, but harder to study. A new study by Ramakrishna et al. uses an exciting new technology, cryo nanoscale secondary ion mass spectrometry ion microprobe, to investigate elemental distribution…

Non-invasive imaging technologies like computed tomography and magnetic resonance imaging (MRI) have revolutionized medicine by improving diagnostics and guiding treatment. Due to its versatility, MRI also holds potential for plant sciences, where it can be used to visualize and quantify metabolites…

Targeting a given protein for degradation at a specific time can be very useful when investigating its function in the cellular context. In this paper, Huang et al. present an inducible protein degradation system tailored for plants, named E3-DART. The system is based on the specific interaction between…

Fifty years ago (1974), Albert Claude, Christian de Duve, and George Palade were awarded the Nobel Prize for their discoveries on the structural and functional organization of the cell, which Claude eloquently framed by writing, “We have entered the cell, the mansion of our birth, and started the inventory…

This is an excellent article to wrap up this year and lead us into the future. Introducing a special issue of Plant Cell Physiology, Nakajima et al. summarize an exciting collection of papers that look at diverse ways that plant biology can be enhanced through “human-machine collaborations”. Some…

Although CRISPR/Cas9 tools have provided new opportunities for genome editing, using these systems to introduce large pieces of DNA has been challenging. A new genome editing technique, “PrimeRoot” (Prime editing-mediated Recombination Of Opportune Targets), was introduced by Sun et al. and shown…