Recent Posts

Improving crops by genome editing

Introducing new desirable traits in domesticated crops takes time and is limited by the need for existing trait variation in members of the same species or closely related species. Rodríguez-Leal et al. propose a system by which variation in a quantitative trait can be generated by editing the promoter…

Low-gluten, non-transgenic wheat engineered with CRISPR/Cas9

Celiac disease is a debilitating autoimmune disease in which antigens in plant gliadins (one type of gluten protein) stimulate production of antibodies that inflame the lining of the small intestine. In wheat, α-gliadin (the main cause of the sensitivity) is encoded by more than 100 genes, thwarting…

Peanuts that keep aflatoxin at bay: A threshold that matters

Aflatoxins are small molecules that are extremely damaging to human health that are produced by the fungal species Aspergillus flavus and Aspergillus parasiticus.  Peanut pods form underground and so are particularly vulnerable to infection by the fungus. Sharma et al. used a two-pronged approach to…

Novel loci underlie natural variation in vitamin E levels in maize grain

Vitamin E (alpha-tocopherol and related tocochromanol compounds) is a lipid-soluble antioxidant that contributes to numerous cellular activities and confers protection against many diseases, from cancer to cardiovascular disease. The main sources of vitamin E for humans are plant oils, but most crop…

Engineering quantitative trait variation for crop improvement by genome editing ($)

Variation is the engine of evolution, and plant breeders and geneticists have long relied on induced variation to create a population from which to select. Rodríguez-Leal et al. used CRISPR/Cas9 mutagenesis to selectively introduce variability into the promoter regions of three genes involved in tomato…

An acidophilic green algal genome provides insights into adaptation to an acidic environment ($)

Hirooka et al. examined the genome of an acid-loving green alga, Chlamydomonas eustigma, to learn how it tolerates its low pH environment. Key differences between the acidophilic species and the neutrophilic species Chlamydomonas reinhardtii include: an increase in expression of genes encoding plasma…

Natural variation of photosynthetic traits for enhanced yield in rice

Natural variation in photosynthetic traits can be exploited for new targets for breeding or genetic engineering of crops. In an effort to identify traits which can lead to enhanced biomass production and therefore yield potential in rice, Qu et al. conducted a comprehensive survey of 14 photosynthetic…

Opinion: Beyond editing to writing large genomes ($)

This is an era of rapid acceleration of our ability to both read and write genomes. Chari and Church point to a future in which making a small number of changes in a genome (editing) is supplanted by making hundreds or thousands or more of changes, essentially whole-genome editing. Basically, the authors…

Review: Cutin from agro-waste as a raw material for the production of bioplastic ($)

When we think about making things from plant biopolymers, we often think about cellulose, the “most common natural polymer on Earth, with an estimated annual biomass production between 1011 and 1012 tons” or ligin, with a biomass production on the order of 107 tons per year. Heredia-Guerrero et al.…