Entries by Sunil K. Kenchanmane Raju

Comparative profiling examines roles of DNA regulatory sequences and accessible chromatin during cold stress response in grasses

July 21, 2020 in , , /by

Physical access to regulatory DNA, including cis-regulatory sequences found within proximal promoters and distal enhancer elements, is a vital property of chromatin.  In turn, their access is determined by nucleosome occupancy and post-translational modification of histone proteins. A continuum of chromatin accessibility states from closed to permissive and open chromatin is a critical determinant of […]

Gene Dosage Balance Immediately Following Whole-Genome Duplication in Arabidopsis thaliana

April 24, 2020 in , , /by

Flowering plants have witnessed multiple cycles of whole-genome duplication (WGD) over the past 200 million years of evolution. Typically, WGD increases genome size and gene content, followed by gene loss, or fractionation, depending on functional categories. Certain classes of genes are retained as duplicates for longer periods of evolutionary time. Duplicate genes provide a potential […]