Crosstalk, crosstalk— it’s a word that keeps coming up. Indeed, and perhaps not surprisingly, plant hormone signaling pathways all seem to affect each other to some extent. For example, the MYC2 transcription factor plays roles in abscisic acid (ABA) and jasmonic acid (JA) signaling in the response to abiotic stress. Moreover, ABA stimulates JA biosynthesis; […]
When plants have plenty of room, they can maximize the incoming light by spreading their leaves. However, in modern agricultural fields, plants that hold their leaves upright to decrease mutual shading can be grown at high density. Leaves serve as a reservoir for nitrogen that can be re-mobilized to developing seeds, thus increasing grain yield, […]
Approaches to improve final grain production must consider yield stability, that is ways to prevent yield losses. For example, flowering time affects yield and yield stability– if grains mature late, they may be literally caught out in the cold, as late-season weather turns. Indeed, the application of nitrogen fertilizer, one of the key drivers of […]
Histones undergo myriad covalent modifications – more than 100 types have been identified in the 50+ years since Allfrey, Faulkner, and Mirsky (1964) found that increased histone acetylation was associated with genomic regions of active transcription (reviewed in Zentner and Henikoff, 2013). Enzymes referred to as “writers” add chemical modifications on DNA or histones and […]
Polarization may be bad for civil discourse, but sometimes polarization can be good—for example, if you’re a multicellular organism setting its body axes. In many organisms, polarity within the zygote sets the stage for an asymmetric cell division that defines the apical-basal polarity of the developing organism (reviewed in Rensing, 2016). In addition to providing […]
The C-terminal domain (CTD) of RNA polymerase II (Pol II) extends from the catalytic core and consists of repeats of a seven-amino acid motif. The CTD functions in the regulation of Pol II function and is subject to just about every protein modification you can think of, including methylation, acetylation, ubiquitination, phosphorylation, and O‑GlcNAcylation (reviewed […]
The assassin who injects a bead of poison by stabbing his victim with the tip of his umbrella has got nothing on plant pathogenic bacteria such as Pseudomonas syringae, which injects dozens of effector proteins into plant cells. These effectors act as tiny assassins to take out host defenses by diverse mechanisms, thus helping the […]
Fans of the television show The Magic Schoolbus might remember that the teacher/heroine, Ms. Frizzle used to tell her students “Your job, as scientists, is to look for connections!” Ms. Frizzle would love the Mos4-associated Complex (MAC), because MAC has connections all over the place. Indeed, research in mammalian systems and Saccharomyces cerevisiae has shown […]
We all know that DNA is the stable nucleic acid, in comparison to its flighty, unstable cousin RNA, right? Well, unusual things happen when metabolic processes require DNA to unwind from its stable, redundant double-helical form. For example, during transcription, the RNA that exits RNA polymerase can pair with the template DNA strand, leaving the […]