Recent Posts

In the Histone Zone: The Mighty Eraser

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Histones undergo myriad covalent modifications - more than 100 types have been identified in the 50+ years since Allfrey, Faulkner, and Mirsky (1964) found that increased histone acetylation was associated with genomic regions of active transcription (reviewed in Zentner and Henikoff, 2013). Enzymes…

A Novel Class of Histone Readers

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Polycomb-group (PcG) proteins are part of an epigenetic memory system that regulates global gene expression throughout development in multicellular eukaryotes (Butenko and Ohad, 2011). Sophisticated mechanisms recruit high molecular weight complexes of PcG proteins to specific targets in the genome.…

The Transition from Postdoc to PI: Part 7 Don't forget - IT IS EXCITING!

Part 7: Don't forget - IT IS EXCITING! by Amanda Rasmussen This has turned into quite a long article based on the advice and insecurities of 8 PIs of varying experience (see details at the end). Our intention is not to scare anyone off making the jump from post-doc to PI…but rather to let you know…

The Transition from Postdoc to PI: Part 6 Academic Imposter Syndrome

Part 6: Academic Imposter Syndrome (AIS- pronounced Ace) by Amanda Rasmussen Academic Imposter Syndrome (AIS): (I’ve decided to call it AIS (pronounced ace) because that sounds more positive) I’m not going to lie, this is something I struggle with on an almost daily basis. There are so…