Yiping Wang, first author of “Arabidopsis MAPKK kinases YODA, MAPKKK3, and MAPKKK5 are functionally redundant in development and immunity”
Current Position: Associate researcher, Hong Kong Baptist University, Hong Kong, China
Education: PhD in Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, China; B.S. in Lanzhou University, China
Non-scientific Interests: Hiking
Brief bio: My research focuses on plant-pathogen interactions and plant heterotrimeric G-protein signaling. The plant development and immunity pathways share many same signaling components, such as the coreceptor BAK1, heterotrimeric G proteins, and MAPK cascade components. In this work, we identified MAPKKK3/4/5 (MAPKKK4 is also known as YODA) as the upstream MAPKKKs for many MKK4/5-MPK3/6-mediated development and immunity pathways. MAPKKK3/4/5 function downstream of pattern recognition receptors (PRRs) to contribute to microbe-associated molecular pattern (MAMP)-triggered MAPK activation and disease resistance. Further studies on how the same MAPKKK3/4/5-MKK4/5-MPK3/6 cascade is differently activated upon various ligand-receptor recognitions and how it triggers different downstream responses, will expand our understanding of multiple development and immunity signaling pathways in plants.