Yiping Wang: Plant Physiology First Author

Yiping Wang, first author of “Arabidopsis MAPKK kinases YODA, MAPKKK3, and MAPKKK5 are functionally redundant in development and immunity”

Current Position: Associate researcher, Hong Kong Baptist University, Hong Kong, China

Education: PhD in Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, China; B.S. in Lanzhou University, China

Non-scientific Interests: Hiking

Brief bio: My research focuses on plant-pathogen interactions and plant heterotrimeric G-protein signaling. The plant development and immunity pathways share many same signaling components, such as the coreceptor BAK1, heterotrimeric G proteins, and MAPK cascade components. In this work, we identified MAPKKK3/4/5 (MAPKKK4 is also known as YODA) as the upstream MAPKKKs for many MKK4/5-MPK3/6-mediated development and immunity pathways. MAPKKK3/4/5 function downstream of pattern recognition receptors (PRRs) to contribute to microbe-associated molecular pattern (MAMP)-triggered MAPK activation and disease resistance. Further studies on how the same MAPKKK3/4/5-MKK4/5-MPK3/6 cascade is differently activated upon various ligand-receptor recognitions and how it triggers different downstream responses, will expand our understanding of multiple development and immunity signaling pathways in plants.

姓名：王益平

目前职位：副研究员，香港浸会大学

教育背景：中国科学院遗传发育所，博士；兰州大学，学士

兴趣爱好：远足

个人简历：本人主要从事植物-病原菌互作和植物异源三聚体G蛋白信号研究。目前已有的研究表明植物很多发育和免疫通路共享了很多信号组分，如共受体BAK1、异源三聚体G蛋白、MAPK级联反应蛋白。本研究鉴定三个重要的MAPKKK，MAPKKK3/4/5功能冗余，作用于MKK4/5-MPK3/6上游，调控多个发育和免疫通路。MAPKKK3/4/5作用于免疫受体下游，调控微生物相关分子模式（MAMP）诱导的MAPK激活。今后研究MAPKKK3/4/5如何特异性地被不同受体激活，并通过相同的MAPK级联反应作出不同的响应，将极大地加深我们对发育和免疫信号机制的了解。