Xiaotong Liu, co-first author of “The calcium-dependent protein kinase CPK28 is targeted by the ubiquitin ligases ATL31 and ATL6 for proteasome-mediated degradation to fine-tune immune signaling in Arabidopsis”
Current Position: Assistant researcher at the Center for Agricultural Resources Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
Education: Ph.D. Crop Science from Chinese Academy of Agriculture Science
Non-scientific Interests: Listening Rock Music, Traveling and Playing with my cat
Brief bio: I joined Prof. Dongping Lu’s lab in Chinese Academy of Sciences when I get my Ph.D. degree from Chinese Academy of Agriculture Science. My research focus on Plant Biotic Interactions. I keep my research interest in understanding the mechanism of plant innate immunity. I find a negative immune regulator CPK28 was tightly regulated by two E3 ligases ATL31 and ATL6. ATL31/6 directly ubiquitinate CPK28, resulting in its proteasomal degradation. Furthermore, ATL31/6 promote the stability of BIK1 by mediating CPK28 degradation. Consequently, ATL31/6 positively regulate BIK1-mediated immunity. Our findings reveal a mechanism for attenuating CPK28 function to maintain BIK1 homeostasis and to enhance immune responses. I hope the finding will contribute to scientific development in this field.