Xiaoqian Chu: The Plant Cell Author

Xiaoqian Chu, co-first author of HBI Transcription Factor-Mediated ROS Homeostasis Regulates Nitrate Signal Transduction

Current Position: Job hunting

Education: PhD in Botany at Shandong University

Non-scientific Interests: Reading, Music, Museums

Brief bio: I started my PhD study and accepted systematic scientific training in Ming-Yi Bai’s laboratory of Shandong University. Since then, I have focused on the function of the transcription factor HBI1. We found that the expression of HBI1 and its homologous gene BEE2 was induced by nitrate. We further proved that mutations of HBI1 and its three most homologous (HBIs) weaken the sensitivity of plants to nitrate in terms of growth and gene expression. HBIs induces the expression of a set of antioxidant genes and reduces the content of reactive oxygen species in plants, while reactive oxygen species and nitrate nitrate antagonize the subcellular localization of NLP7, a key transcription factor that regulates nitrate signal transduction, thereby regulating downstream gene expression and plant growth and development.






科研经历: 我在山东大学白明义教授实验室攻读的博士学位,接受了系统的科学训练。从那时起我开始研究油菜素内酯信号通路下游转录因子HBI1的功能。我们发现HBI1及其同源基因BEE2受到硝态氮的诱导表达。我们通过实验证明,突变HBI1及其最同源的三个基因(HBIs)减弱了植物对硝态氮的敏感性。HBIs诱导活性氧清除基因的表达,从而降低了植物体内的活性氧含量。我们还发现活性氧与硝态氮拮抗调控硝态氮信号转导关键转录因子NLP7的亚细胞定位,从而调控了下游基因的表达和植物的生长发育。