Xiaochang Yin, co-first author of “Binding by the Polycomb complex component BMI1 and H2A monoubiquitination shape local and long-range interactions in the Arabidopsis genome”
Current Position: Postdoc, School of Advanced Agricultural Sciences, Peking University, China
Education: Ph.D., Hainan University, China
Non-scientific Interests: travelling
Brief bio: During my Ph.D. study, I worked in Professor Xingyu Jiang’s lab, mainly to dissect the molecular mechanisms underlying plant salt tolerance. In the postdoc stage, I joined Dr. Yue Zhou’s lab in Peking University in 2020. I studied plant epigenetics, with a main focus on the molecular mechanism of Polycomb Group (PcG) proteins regulating chromatin structure in Arabidopsis. In this work, we show that Arabidopsis genome is partitioned into contiguous compartment domains (CDs) with different epigenetic features. The histone-modifying Polycomb group machinery has been involved in 3D chromatin organization, which is required to maintain appropriate intra-CD and long-range interactions.
个人简介：博士期间我加入江行玉教授课题组，从事植物响应逆境胁迫的功能研究。2020年我有幸加入北京大学周岳研究员课题组开展博士后研究工作，从事植物表观遗传学研究，尤其关注Polycomb Group (PcG) 蛋白调控的抑制机制在植物发育中的作用。本研究中我们发现拟南芥基因组可以划分为带有不同表观修饰的区室结构域(CD)，PcG蛋白参与拟南芥基因组局部和远程相互作用的调控。