Enhanced super-resolution ribosome profiling unveils pervasive translation of upstream ORFs and small ORFs in Arabidopsis
Plant Science Research WeeklyIn recent years, the discovery that the translational regulation of many mRNAs is influenced by small upstream open reading frames (uORFs) has highlighted the importance of precisely identifying gene structures and translated ORFs to understand gene functions and cellular behavior. Using Arabidopsis,…
RNA hairpins underlie preferential use of translation start codons
Plant Science Research WeeklyGene expression regulation facilitates environmental adaptation and survival. This recent paper by Xiang et al. focuses on the regulation of translation, in particular on the mechanism underlying the generation of different translation products in different conditions. In addition to the main start codon…
A tug-of-war in the viral replication factory: How a viral protein interferes with stress granules
The Plant Cell: In a NutshellHoffmann et al. explore replication of Cauliflower mosaic virus and how virus replication intersects RNA granule biology.
https://doi.org/10.1093/plcell/koad101
Gesa Hoffmann and Anders Hafrén, Swedish University of Agricultural Sciences
Background: Regulating RNA abundance and its availability…
Cauliflower mosaic virus uses Arabidopsis RNA processing body components to its advantage
The Plant Cell: In a NutshellHoffmann et al. discover how Arabidopsis RNA processing body components are co-opted by Cauliflower mosaic virus to evade translational repression.
By Gesa Hoffmann and Anders Hafrén, Swedish University of Agricultural Sciences
Background: Viruses are unique in their ability to reuse and recycle…