Recognizing The Plant Cell author Yingying Xing

Yingying Xing, first author of Bacterial effector targeting of a plant iron sensor facilitates iron acquisition and pathogen colonization

Current Position: Ph.D. graduate

Education: Ph.D. in Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, China; Bachelor in College of Plant protection, Northwest A&F University, Yangling, Shaanxi, China.

Non-scientific Interests: listening music, running, reading

Brief bio:  In 2013, I started my graduate study at the Institute of Microbiology, Chinese Academy of Sciences under the supervision of Prof. Jun Liu. My PhD project focused on the molecular mechanism of plant-microbe interaction. We found that AvrRps4, an effector protein secreted by a bacterial pathogen Pseudomonas syringae, interacts with and targets the plant iron sensor protein BRUTUS (BTS), resulting in increased iron accumulation in the plants and enabling iron uptake by Pst. BTS is also important for accumulating immune protein EDS1 upon Pst (avrRps4) infection and contributes to RPS4/EDS1-mediated immune responses. Although effector proteins secreted by pathogenic bacteria have been shown to act in a variety of biological processes, this is the first study to show that an effector can manipulate host iron homeostasis. I was lucky to get the great help from Dr. Ning Xu of our research group, and finally published it in The Plant Cell. Now, I will be a postdoc at College of Plant protection, China Agricultural University. My research interest is the plant nutrition and immunity.




教育背景:2013/09-2020/12 中国科学院微生物研究所,博士

2009/09-2013/07 西北农林科技大学,植物保护学院,学士

兴趣爱好:听音乐,跑步, 阅读

个人研究简介:2013年进入中国科学院微生物研究所刘俊课题组硕博连读,主要研究方向是植物与微生物互作的分子机制。在博士期间的研究工作中,我们发现了丁香假单胞菌分泌的效应蛋白AvrRps4能够靶向植物的铁响应调控蛋白BTS,并干扰BTS对下游铁响应因子PYEL类蛋白的降解,从而促进植物对铁的吸收和病原菌的增殖。同时,BTS能够促进免疫响应蛋白EDS1的积累,参与RPS4/ EDS1介导的免疫应答。虽然病原菌分泌的效应蛋白已被证明可以作用于多种生理过程,但这项研究第一次显示了效应蛋白可以操纵寄主铁的稳态。非常感谢课题组徐宁博士的帮助,使得这项研究最终能够成功发表在The Plant Cell。我将在中国农业大学植物保护学院做博士后, 研究方向是植物营养与免疫。