Recognizing Plant Physiology author Guichen Li

Guichen Li, first author of Mitochondrial Heat Shock Cognate Protein 70 Contributes to Auxin-mediated Embryo Development

Current Position: Ph.D. candidate, College of Life Sciences, Nankai University

Education: 2012/09-2016/07: Bachelor in College of Life Sciences, Lanzhou University; Since 2016/09: Master and Ph.D. in College of Life Sciences, Nankai University

Non-scientific interests: Badminton and cooking

Brief bio: I joined the College of Life Sciences, Nankai University in 2016 and studied for a master’s degree under the guidance of Professor Shuzhen Men. In 2019, I became a PhD student in Men Lab. During this period, we focused on the biological function of the mitochondrial heat shock protein mtHSC70 in Arabidopsis. Under the guidance of my advisor, we found that mtHSC70-1 deficiency leads to defective embryo development, and the embryo defect was associated with reduced or ectopic expression of auxin responsive reporter DR5rev:GFP. On the other hand, mitochondrial retrograde regulation (MRR) was enhanced in mthsc70-1, and treatment with an inhibitor which activates mitochondrial retrograde signaling reduced the expression level of auxin biosynthesis and polar auxin transport genes and induces similar phenotypes as that in the mthsc70-1b. Taken together, our data reveal that loss of function of mtHSC70-1 induces MRR, which inhibited auxin biosynthesis and polar auxin transport, leading to abnormal auxin gradients and defective embryo development. This finding shedding light on the underlying mechanism of mtHSC70 regulated reproductive development in Arabidopsis.



教育背景:2012/09-2016/07 兰州大学,生命科学学院,学士

2016/09至今 南开大学,生命科学学院,硕士和博士