Recognizing Plant Cell authors: Yuan Xie

Yuan Xie, co-first author of Photosynthetic Phosphoribulokinase Structures: Enzymatic Mechanisms and the Redox Regulation of the Calvin-Benson-Bassham Cycle

Current Position: Postdoctoral Associate in Department of Biophysics, Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China

Research Experience: Postdoctoral Associate in Weill Cornell Medicine College, New York, NY, USA, Supervisor: Prof. Crina Nimigean

Education: Ph.D. in National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, Supervisor: Prof. Wenrui Chang and Prof. Mei Li

Non-scientific interests: music, movies, traveling, and reading

Brief bio: During my master’s and Ph.D. degree, I developed a strong interest in biophysics. Through x-ray crystallography and cryo-electron microscopy, high-resolution structures of the proteins can be obtained. By systematically analyzing the structure of proteins, the mechanism and the regulation mode of the target protein could be revealed. My research focused on photosynthesis and related proteins, including photosynthetic membrane proteins and enzymes involved in photosynthesis. After that, my post-doc work mainly includes the structure and regulatory mechanism of ion channels and transporters. Human ion channels and transporters are ubiquitous membrane proteins, which are vital to cellular processes such as cell membrane excitability, propagation of nervous stimuli and molecule transport. Defects in these proteins can alter their function and regulation, which can lead to an imbalance in the cell homeostasis and even human disease. A detailed study of these proteins can provide us with more information to reduce the occurrence and development of diseases.




科研经历:博士后,威尔·康奈尔大学医学院,美国纽约,Crina Nimigean教授实验室