Xiaowen Shi, first author of Genomic imbalance determines positive and negative modulation of gene expression in diploid maize
Current Position: Postdoctoral Fellow in the Division of Biological Sciences at University of Missouri, Columbia
Education: Ph.D. in Genetics, Genomics and Development, Cornell University, USA; B.S. in Biological Sciences, Zhejiang University, China
Non-scientific Interests: traveling, running, baking
Brief bio: I have always had a great interest in plant genetics. I joined Dr. Maureen Hanson’s lab at Cornell University for my graduate study, where I identified and characterized a few genes involved in C-to-U RNA editing in chloroplasts and mitochondria in Arabidopsis. These findings expand our knowledge of the composition of the RNA editosome and how it operates. Later, I became interested in learning bioinformatics and computational biology and began to work as a postdoc at University of Missouri in Dr. James Birchler’s lab. Currently, my research focuses on understanding the mechanism of genome imbalance induced by aneuploidy in maize via mRNA-seq and sRNA-seq. Meanwhile, I am also interested in developing tools and methods that favor the analysis of aneuploidy and polyploidy to facilitate the study of genome imbalance.
个人研究简介：我一直对植物遗传学有非常浓厚的兴趣。我的博士生导师是美国康奈尔大学的Maureen Hanson教授。在她的指导下，我发现了一些参与拟南芥叶绿体和线粒体C-to-U RNA编辑的基因, 并研究了这些基因的功能和相互作用。这极大地丰富了大家对RNA编辑复合体及其相关机制的了解。在美国密苏里大学James Birchler院士实验室做博后期间，我对生物信息学和计算生物学产生了兴趣。目前我主要通过mRNA和sRNA测序来研究玉米内由染色体数目异常引起的基因组不平衡的相关机制。同时，我也致力于开发关于研究非整倍体和多倍体材料的基因组学方法。希望这些新的方法能促进基因组不平衡领域的研究发展。