Chenhao Bu: Plant Physiology First Author
Chenhao Bu, co-first author of “Enhanced genome-wide association reveals the role of YABBY11-NGATHA-LIKE1 in leaf serration development of Populus”
Current Position: National Engineering Laboratory for Tree Breeding, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants, doctoral candidate
Education: Shandong Normal University (Bachelor)
Beijing Forestry University (Ph.D. candidate)
Non-scientific Interests: Football, boxing
Brief bio: In 2016, I start my research under supervision of Prof. dr. Yuepeng Song and Prof. dr. Deqiang Zhang, in the Collage of Biological sciences and technology, Beijing Forestry University. My research using poplar as a model for perennial woody plants and mainly focus on the effect of genetic variation at the population level on photosynthetic phenotypes and functional verification of miniature inverted repeat transposable element.
In this study, a combined GWAS and eQTN mapping applied to create a leaf morphology control module using data from Populus tomentosa and Populus simonii populations. YABBY11 was identified as a positive regulator of leaf margin serration. In P. tomentosa, PtoYAB11 carries a premature stop codon (PtoYAB11PSC), resulting in the loss of its positive regulation of NGATHA-LIKE1 (PtoNGAL-1) and RIBULOSE BISPHOSPHATE CARBOXYLASE LARGE SUBUNIT (PtoRBCL). Overexpression of PtoYAB11PSC promoted serrated leaf margins, enlarged leaves, photosynthesis, and increased biomass. Overexpression of PsiYAB11 in P. tomentosa promoted smooth leaf margins, stomatal density, and light damage repair ability. In poplar, YAB11-NGAL1 is sensitive to environmental conditions and acts as a positive regulator of leaf margin serration; it may also link environmental signaling to leaf morphological plasticity.
姓名：卜琛皞
目前职位：北京林业大学生物科学与技术学院在读博士
教育经历：北京林业大学（硕博连读）
山东师范大学（学士）
非学科兴趣：足球，拳击
个人简历：本人于2016年进入北京林业大学攻读研究生，师从张德强教授和宋跃朋教授，硕博期间从事林木基因组学和群体遗传学研究。该研究利用全基因组关联分析和数量性状定位的方法鉴定到与叶形变异显著相关的基因YABBY11。基因结构解析发现毛白杨基因组中该基因提前终止，该自然变异的存在是毛白杨叶片边缘锯齿形成的重要原因之一。在小叶杨和毛白杨中过表达该基因能够调控叶片形态建成，使叶缘更光滑，并提高气孔密度以及光损伤修复能力。实验证明YAB11能够结合在PtoNGAL1和PtoRBCL基因的启动子区域并调控其表达，而且YAB11-NGAL1复合体能够抑制CUC2基因的表达来调节叶片形态建成。本研究对杨树叶片形态建成提供了新的见解。
