Entries by Yadukrishnan Premachandran

PIFs link environmental changes with chromatin dynamics (Nature Genetics)

PHYTOCHROME INTERACTING FACTORS (PIFs) play a pivotal role in mediating the responses of plants to various environmental stimuli. Although the importance of PIFs in shade avoidance response is well known, the relative contributions of different PIFs have not been discretely determined. In a recent study, Willige et al. identified that among the PIFs, PIF7 acts […]

A TOTally new pathway regulating thermomorphogenesis (Nature Comms)

Increase in ambient temperature often causes remarkable changes in the shape and organization of plant body, including elongation of hypocotyl and petioles, early flowering, and reduction in stomatal index, collectively known as thermomorphogenesis. Virtually all the molecular pathways that are known to regulate thermomorphogenesis act through the light signaling factor PHYTOCHROME INTERACTING FACTOR4 (PIF4). PIF4 […]

Who keeps PIF4 high on a hot day? RCB joins HEMERA as a partner in crime (Nature Comms)

PHYTOCHROME INTERACTING FACTOR4 (PIF4) is a key protein that mediates thermomorphogenic responses in plants. Under warm temperatures, PIF4 levels are high in the daytime even in the presence of active phyB, which is known to induce degradation of PIFs. Thus, in warm temperatures there must be a mechanism that circumvents the phyB-mediated degradation of PIF4. […]

A complementary mechanism to the microRNA-mediated control of leaf size (Plant Physiol)

Plants form leaves with highly reproducible sizes and shapes by employing a conserved set of developmental regulators. During early leaf growth, a zone of high cell proliferation is formed towards the proximal end of the lamina.  Proliferating cells progressively exit this zone and enter the distal half of the lamina where cell expansion and differentiation […]

A novel hyperactive UVR8 variant for enhanced UV-B responses (PNAS)

Plants perceive UV-B radiation using a specialized photoreceptor protein called UVR8. Upon UV-B exposure, activated UVR8 initiates a signaling cascade, inducing a range of morphological and biochemical responses that facilitates UV adaptation. In a mutagenesis screen, Podolec et al. identified a mutant named uvr8-17D, which produces a hyperactive variant of UVR8, harbouring a glycine-101 to […]

Review: Age is NOT just a number (Trends Plant Sci)

Aging of plants is marked by the growth and differentiation of individual organs, as well as transitions of the whole plant through developmental phases: juvenile, vegetative adult, and reproductive phase. In their recent review, Rankenberg et al. discuss how abiotic stress responses vary in plants with their age. Spatiotemporally regulated and meticulously coordinated action of […]

BONZAIs emerge as nodal regulators of osmotic stress responses (Curr. Biol.)

Plants launch their response to osmotic stress with a sudden spike in cytosolic Ca2+ levels, which subsequently leads to the accumulation of the phytohormone abscisic acid (ABA). This further initiates a chain of events including closure of stomata, large-scale transcriptional changes, retardation of overall growth, and the onset of early senescence. However, the mechanism by […]

Shade avoidance or shade tolerance? The balancing act of PIF-HFR1 module (EMBO J.)

Plants have evolved two major adaptive strategies to tackle shade from their neighbours: avoidance and tolerance. However, what makes a species shade-avoider or shade-tolerant at the molecular level has remained mostly elusive. Recently, Paulisic et al. uncovered the key role of a regulatory module formed by PHYTOCHROME INTERACTING FACTORS (PIFs) and LONG HYPOCOTYL IN FR1 […]

A novel GUN1-independent retrograde signaling pathway represses photomorphogenesis (Plant Physiol.)

Seedlings emerging in light undergo photomorphogenic development, forming short hypocotyls and green, fully opened cotyledons. Disruption of chloroplast development by drugs such as lincomycin induces retrograde signals (RS) that inhibit photomorphogenesis. The retrograde signaling pathway has been known to act primarily through the chloroplast-localized master regulator protein GENOMES UNCOUPLED1 (GUN1). Now, Gommers et al. reveals […]