Deubiquitinating enzymes UBP12, 13 are antagonistic to E3 ligases BIG BROTHER and DA2 (eLIFE)
Post-translation modifications like ubiquitination and deubiquitination are important to maintain protein homeostasis and in turn plant growth. DA1, and DA1-RELATED PROTEIN 1, 2 (DAR1, DAR2) are latent peptidases activated upon ubiquitination by E3 ligases BIG BROTHER (BB) and DA2. In this paper, Vanhaeren et al. identified UBIQUITIN BINDING PROTEIN 12, 13 (UBP12, 13) as the […]