The PHO1 protein family in phosphate export and beyond
Abstract The Arabidopsis thaliana PHOSPHATE 1 (PHO1) was first identified as an inorganic phosphate (Pi) exporter mediating Pi loading into the root xylem. PHO1 is the prototypical member of a family of eukaryotic proteins possessing both an SPX and EXS domain. Recent cryo-EM structures of both the Arabidopsis PHO1 homologue PHO1;H1 and its mammalian orthologue Xenotropic and Polytropic…