Recent Posts

An inducible protein degradation system for rapid depletion of target proteins

Targeting a given protein for degradation at a specific time can be very useful when investigating its function in the cellular context. In this paper, Huang et al. present an inducible protein degradation system tailored for plants, named E3-DART. The system is based on the specific interaction between…

The CLP and PREP protease systems coordinate maturation and degradation of the chloroplast proteome in Arabidopsis thaliana (New Phytol.)

The ATP-dependent CLP chaperone-protease system is a crucial part of the peptidase network required to maintain proteostasis in the Arabidopsis chloroplast. Its substrates include misfolded and aggregated proteins of any size, and it is essential for plant growth and development. PREP1,2 peptidases are…