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Cytokinin–CLAVATA cross-talk is an ancient mechanism regulating shoot meristem homeostasis in land plants (PNAS)

The shoot apical meristem (SAM) maintains a small pool of pluripotent stem cells, which are the source of all above-ground plant tissues. In Arabidopsis thaliana, CLAVATA3 (CLV3), CLAVATA1(CLV1) and RECEPTOR-LIKE PROTEIN KINASE2 (RPK2) repress WUSCHEL (WUS) expression. WUS induces CLV3, forming a local…