Shuyan Song: The Plant Cell First Author

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Shuyan Song, first author of “The functional evolution of architecturally different plant geranyl diphosphate synthases from geranylgeranyl diphosphate synthase” 

Current Position: Postdoctoral Fellow in State Key Laboratory of Rice Biology, College of Agriculture and Biotechnology & ZJU‐Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou

Education：2017-2022 Ph.D in Nanjing university; 2013-2015 MS in Huazhong Agricultural University; 2009-2013 BS in Huazhong Agricultural University

Non-scientific Interests: Musical, reading; cycling

Brief bio: I joined Prof. Shan Lu’s lab at Nanjing University for a PhD project about the functional evolution of the plant GGPPS family. Previous research of LuLab discovered the multifaceted functions of GGPPS family members in supplying and branching GGPP metabolite flux for terpenoids synthesis, and different strategies were adopted by rice and pepper GGPPS homologs to produce GPP. We wondered the functional evolution of the plant GGPPS family members and how they evolved to produce GPP. By combining phylogenetic analysis with functional characterization of GGPPS homologs from a wide range of photosynthetic organisms, we investigated how different GPPS architectures have evolved within the GGPPS protein family. Our results reveal that GGPPS gene family expansion and functional divergence began early in nonvascular plants, and that independent parallel evolutionary processes gave rise to homomeric and heteromeric GPPSs. Our study elucidated an evolutionary path for the formation of GPPSs with different architectures from GGPPSs and uncovered the molecular mechanisms involved in this differentiation. After graduation, I joined Prof. Ronghui Pan’s lab to investigate the lineage-specific metabolites produced via peroxisomes in rice, and develop strategies for the plant peroxisome engineering modification.

姓名：宋书言

目前职位：浙江大学杭州国际科创中心/浙江大学农业与生物技术学院，博士后。

教育经历：南京大学，博士；华中农业大学，硕士；华中农业大学，学士。

兴趣爱好：音乐剧，阅读，骑车。

个人简介：我于2017年加入南京大学卢山老师课题组攻读博士学位，围绕植物GGPPS家族的功能演化机制展开研究。实验室之前的研究发现在水稻和辣椒中，GGPPS家族成员不仅参与GGPP的合成与代谢分流，也采用不同的模式负责GPP的供应，于是我们好奇植物GGPPS家族的功能演化及其参与GPP合成的分子机制。通过将系统发育分析与功能表征相结合，我们研究多个物种中植物GGPPS基因家族的功能，发现该家族的扩增和功能分化在非维管植物中就开始了，并且独立演化出同源聚体和异源聚体两种结构的GPPS，我们阐明了植物GPPS形成的演化路径，并揭示其功能演化的分子机制。博士毕业后，我加入浙江大学潘荣辉老师课题组从事博士后研究，接下来我将对水稻过氧化物酶体介导的特有次生代谢物合成机制，以及植物过氧化物酶体工程改造展开研究。