Recognizing Plant Physiology first authors: Juan He

Juan He, first author of Genome-wide transcript and small RNA profiling reveals transcriptomic responses to heat stress

Current Position: Postdoctoral fellow in the group of Prof. Xuemei Chen, Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University

Education: Ph.D. in Plant Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences; B.S. in Biology Science, Shaanxi Normal University, Xi ‘an, China

Non-scientific Interests: Reading, travelling, running, yoga, and playing the flute

Brief bio: After I received my bachelor’s degree in Biology Science in Shaanxi Normal University in 2010, I was recommended to Institute of Plant Physiology and Ecology, Chinese Academy of Sciences (SIPPE, CAS) for a Ph.D. program. I was so lucky to join Prof. Weihua Tang’s lab, studying on the interaction between plants and microbe. My PhD project was to investigate the molecular mechanisms of interaction between maize and a fungus Fusarium graminearum. We found that F. graminearum employed betaine lipid synthase (BTA1) to produced non-phosphorus DGTS (betaine lipid diacylglyceryl-N,N,N-trimethylhomoserine) (instead of phosphatidylcholine) for use in membrane lipids to overcome the phosphate limitation during early apoplastic infection stage in maize stalk (Yan et al., 2016). After obtaining my Ph.D. degree in 2016, I continued my study as a postdoc with Prof. Xuemei Chen in College of Life Sciences and Oceanography, Shenzhen University, working on functions of small RNAs in maize under stress. Among these studies, we provided a comprehensive expression profiling of heat-responsive mRNAs and sRNAs and sheds light on the molecular mechanisms that regulate heat stress in maize at the transcriptional and posttranscriptional levels. I’ll go on further research in the molecular functions of maize miRNAs later.






个人简介:我在2010年本科毕业于陕西师范大学生物科学专业,之后被保送至中科院上海植物生理生态研究所进行硕博连读项目。我非常幸运能够进入唐威华教授的课题组,从事研究植物和微生物的关系。我的博士课题具体是研究玉米和一种真菌禾谷镰孢菌互作的分子机制。我们研究发现禾谷镰孢菌在侵染玉米茎部的早期利用BTA1来合成不含磷的膜脂分子DGTS(betaine lipid diacylglyceryl-N,N,N-trimethylhomoserine) (而不是磷脂酰胆碱)作为其细胞膜的成分,从而适应玉米细胞质外体的低磷环境 (Yan et al., 2016)。在2010年获得博士学位后我进入陈雪梅教授在深圳大学生命与海洋科学学院的团队,研究玉米在逆境中小RNA的功能。其中,我们利用转录组和小RNA文库分析得到了玉米在高温胁迫后mRNA和小RNA转录水平的总体响应,阐明玉米在转录和转录后水平对高温响应的分子机理。后续,我将继续深入研究玉米中miRNA的功能。