Recognizing Plant Physiology first authors: Jilin Chen
Jilin Chen, co-first author of An essential role for miRNA167 in maternal control of embryonic and seed development
Current Position: Postdoctoral Fellow at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
Education: 2011-2017, Ph. D. College of Life Sciences, Xiamen University; 2015-2017, visiting graduate student. Cell and Developmental Biology, University of California San Diego
Non-scientific Interests: travelling and music
Brief bio: I conducted my Ph.D work at Dr. Liang Chen’s laboratory, College of life science, Xiamen University, China. During my graduate study, I received a scholarship from the Chinese Scholarship Council and joined Professor Yunde Zhao’s laboratory at University of California San Diego (UCSD) as a visiting graduate student. At UCSD, I modified CRISPR/Cas9 gene editing technology and was able to efficiently edit genes in Arabidopsis. After graduation, I joined Dr. Shilai Bao’s laboratory at the Institute of Genetics in China. My current research focuses on the roles of PRMT7 in lung development.
陈继林, 第一作者 An essential role for microRNA 167 genes in maternal control of embryonic and seed development
目前职位: 博士后, 中国科学院遗传与发育生物学研究所
教育经历: 2011-2017 厦门大学, 博士生; 2015-2017 加州大学圣地亚哥分校,访问交流博士
兴趣爱好: 旅行和音乐
本人简介: 博士期间我的专业是细胞生物学,在这期间在厦门大学学习了遗传学和分子生物学相关实验技术。随着基因编辑在2013年得到应用以来,我对其在植物中的应用非常感兴趣。于是凭借出国交流学习的机会,我进入赵云德教授团队对Crispr/Cas9在植物中的应用进行改进。我认为随着基因编辑在植物领域中获得广泛应用,植物科学将会有更多的突破。
以往研究报道MIR167s与拟南芥生长素信号通路和稳态高度相关。在这个项目中,我使用了实验室之前开发的Crispr/Cas9系统,有效的在拟南芥中获得了MIR167基因家族的完全敲除突变体。我发现MIR167A在花药开裂和胚珠发育方面存在缺陷。此外,我们还发现了一些未报道的新表型。我们的实验结果清楚地阐明了MIR167A通过ARF6和ARF8在调控拟南芥繁殖过程中起到主要作用。