Recognizing Plant Cell authors: Yan Yan
Yan Yan, first author of MYB30 Is a Key Negative Regulator of Arabidopsis Photomorphogenic Development that Promotes PIF4 and PIF5 Protein Accumulation in the Light
Current Position: Post-doc, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
Education: Ph.D. from China Agricultural University /College of Biological Sciences, Beijing, China; Bachelor’s degree from Nanjing Agricultural University /College of Agro-Grassland Sciences, Nanjing, China
Non-scientific Interests: music, traveling, reading, raising cats
Brief bio:
After completing my undergraduate studies at Nanjing Agricultural University in 2014, I joined Dr. Jigang Li’s lab at China Agricultural University to pursue my PhD degree. Dr. Li’s lab is interested in light signaling and light control of plant responses to abiotic stresses, and my first project was to screen for new transcription factors that interacted with phytochromes. We identified that MYB30, an R2R3-MYB family transcription factor, interacts with phyA and phyB and plays an essential role in regulating phytochrome-PIF signaling networks. We revealed that MYB30 acts to promote PIF4 and PIF5 protein accumulation in the light by directly binding to their promoters to induce their expression, and by inhibiting the interaction of PIF4 and PIF5 with the active form of phyB. The role of MYB30 in phytochrome signaling is likely to maintain the homeostasis of PIF4 and PIF5 levels in plants and prevent an exaggerated response by plants to prolonged light exposure. I am now working as a post-doc in Dr. Xiaofeng Cao’s lab exploring how light and temperature shape the plant epigenome, and hope to make new exciting discoveries in the near future.
姓名：闫延
当前职位：中国科学院遗传与发育生物学研究所博士后
教育经历：2014-2019，中国农业大学生物学院，植物学专业，博士；2010-2014，南京农业大学草业科学学院，草业科学专业，本科
兴趣爱好：音乐、旅行、阅读、养猫
个人简介：
我2014年从南京农业大学本科毕业后，进入中国农业大学生物学院李继刚教授实验室攻读博士学位。李继刚教授实验室主要从事植物光信号转导及逆境响应机制的研究。我通过筛选与光敏色素互作的转录因子，鉴定到一个植物光形态建成的新调控因子MYB30。MYB30是R2R3-MYB家族的转录因子，能够与phyA和phyB相互作用，并且在调控光敏色素-PIFs信号网络中发挥重要的功能。本研究揭示MYB30在光下促进PIF4/PIF5基因的表达，并且抑制Pfr形式的phyB与PIF4/PIF5的相互作用。通过这两个调控机制，MYB30促进PIF4/PIF5在长时间光照条件下的蛋白积累，从而维持PIF4/PIF5在植物体内的动态平衡，防止植物对长时间光照做出过度反应。我目前在中科院遗传与发育生物学研究所曹晓风院士课题组进行博士后研究，探索植物表观遗传对光和温度的响应机制，期待在不远的将来能够有新的重要发现。
