Mediator CKM and MUTE-ICE1/SCRM2 reinforce auxin responsiveness to sustain MUTE expression during stomatal lineage differentiation
Abstract MUTE functions as a pivotal transcription factor that governs the transition from self-renewal to differentiation in meristemoids during stomatal development. This transition requires MUTE expression to reach a critical threshold, yet the mechanisms that maintain its expression homeostasis remain unclear. Here, we show that the Mediator CDK8 kinase module (CKM) acts as a transcriptional…