Lifan Sun, first author of “TOUCH 3 and CALMODULIN 1/4/6 cooperate with calcium-dependent protein kinases to trigger calcium-dependent activation of CAM-BINDING PROTEIN 60-LIKE G and regulate fungal resistance in plants”
Current Position: Research Assistant, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
Education: Ph. D. candidate, Institute of Microbiology, Chinese Academy of Sciences
Non-scientific Interests: Running, Making handicrafts
Brief Bio: After graduating with a Master’s degree in 2016, I joined Jie Zhang’s research group in the State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences. I knew about plant immune system for the first time here. During the whole life cycle, plants face the challenge of invasion by pathogens, including bacteria, fungi, viruses, insect vectors and etc. Upon pathogen infection, plants immediately activate immune responses to defend against pathogens and protect themselves. Plant cells seem to be delicate, but they are equipped with sophisticated immune systems. This amazes me and catches my interests in the study of plant immune mechanisms. I take the plants as my good friends as if I can feel the wonderful life of each plant, which makes me not alone in scientific research.
Calcium ion serves as an important second messenger in eukaryotes and regulates diverse cellular responses. Cell-surface and intracellular receptors are employed by plant cells to sense microbes and activate calcium influx. The mechanisms through which plants decipher calcium influx to regulate downstream immune responses remain largely unknown. Our study revealed cooperative interconnections between different types of calcium sensors in plants, uncovering a novel calcium signal decoding mechanism during plant immunity.
论文：TOUCH 3 and CALMODULIN 1/4/6 cooperate with calcium-dependent protein kinases to trigger calcium-dependent activation of CAM-BINDING PROTEIN 60-LIKE G and regulate fungal resistance in plants