Jiaqi Hou: Plant Physiology First Author

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Jiaqi Hou, first author of “The Histone Deacetylase 1/ GSK3/SHAGGY-Like Kinase 2/ BRASSINAZOLE RESISTANT 1 Module Controls Lateral Root Formation in Rice”

Current Position: PhD Student, College of Life Sciences, Wuhan University

Education: B.S., School of Life Science and Technology, Wuhan Polytechnic University

Non-scientific Interests: Football, Badminton, Traveling, Movies

Brief bio: Since 2018, I joined the research group of Prof. Lijia Li in the State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, to start my PhD study. During the period, I mainly focused on studying how histone acetylation modifying enzymes, phosphorylation modifying enzymes and other epigenetic modifying proteins participate in the growth and development of rice and respond to abiotic stress processes.

In this research article published in Plant Physiology, we reported that histone deacetylase OsHDAC1 can participate in the BR signaling pathway to regulate the initiation of lateral root primordia and affect the formation of lateral roots. In addition, as for how the modification enzymes related to the histone acetylation level can regulate the transcriptional activation and inhibition of related trait genes by changing the acetylation level at the whole genome level, I am currently trying to use molecular biology, biochemistry and omics combined with sequencing technology to clarify molecularly how they change the chemical modification of histones at specific sites, reveal the related genes affected by the modification level of these sites, and elucidate the regulatory mechanisms.

姓名：侯佳启

当前职位：武汉大学 生命科学学院 博士生

教育背景：武汉轻工大学 生命科学与技术学院 学士

兴趣爱好：足球， 羽毛球，旅行，电影

个人简历：本科毕业之后，我加入了武汉大学生命科学学院杂交水稻国家重点实验室李立家教授课题组开始硕博连读。期间，我主要聚焦于研究组蛋白乙酰化修饰酶和磷酸化修饰酶等表观修饰蛋白怎样参与水稻生长发育以及应对非生物胁迫过程。

在Plant Physiology发表的这篇论文中，我们报道了组蛋白去乙酰化酶OsHDAC1能够参与BR信号通路调控侧根原基起始从而影响侧根形成。此外，至于组蛋白乙酰化水平相关修饰酶在全基因组水平如何通过改变乙酰化水平的变化调控相关性状基因的转录激活和抑制，我目前利用分子生物学、生物化学和组学联合测序技术正在试图从分子上阐明他们怎样改变特异位点的组蛋白化学修饰并揭示这些位点的修饰水平改变所影响的相关基因，揭示相关调控机理。