Huijie Liu: The Plant Cell First Author

Huijie Liu, co-first author of “N4-acetylation of cytidine in (m)RNA plays essential roles in plants” 

Current position: Ph.D. candidate, Nanjing Agricultural University

Education: Master, Hangzhou Normal University

Non-scientific Interests: traveling and watching movies

Brief bio:

In 2022, I obtained my master’s degree from Hangzhou Normal University, and then join to Prof. Dr. Mingjia Chen’s lab at Nanjing Agricultural University where I pursue my Ph.D. study focusing on the identification and characterization of RNA modification in plants. In this project, we demonstrate the wide occurrence of cytidine N4-acetylation (ac4C) on mRNAs from various vascular plants. Using acRIP-seq, we mapped the distribution of ac4C modifications in Arabidopsis thaliana. Several lines of evidences showed that N-ACETYLTRANSFERASEs FOR CYTIDINE IN RNA 1 (ACYR1) and ACYR2 are partially redundant and together responsible for RNA acetylation in Arabidopsis. In the future, I will continue my work on the functional analysis of RNA modification in plant and strive to make some new progress in this field.

姓名:刘慧婕

发表论文:N4-acetylation of cytidine in (m)RNA plays an essential role in plants

目前职位:南京农业大学,博士生

教育经历:杭州师范大学,硕士学位

兴趣爱好:旅游,看电影

个人简历:

我于2022年在杭州师范大学获得硕士学位,同年进入南京农业大学生命科学学院陈铭佳课题组攻读博士学位,主要从事RNA新型化学修饰功能解析工作。

我们的研究证实了高等植物mRNA中广泛存在胞嘧啶乙酰化(ac4C)修饰。利用acRIP-seq,我们绘制了拟南芥叶片ac4C修饰图谱。生化和生理实验结果证明植物RNA乙酰化酶ACYR1和ACYR2部分功能冗余,共同介导全局ac4C修饰。未来,我将继续从事RNA修饰功能解析工作,努力在这一领域取得新进展。