Huan Long: Plant Physiology First Author
Huan Long, first author of “Structural and functional regulation of Chlamydomonas lysosome-related organelles in response to environmental changes”
Current Position: Associate professor, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, 430072, China.
Education:
2005/09–2011/06, Ph.D. from Huazhong Agricultural University, Wuhan, China. (2009/09–2010/09, joint PhD student, University of Freiburg, Germany)
2001/09–2005/06, BSc. from Huazhong Agricultural University, Wuhan, China.
(2003/03—2005/06, second BSc. from Wuhan University)
Non-scientific Interests: reading, cooking
Brief bio:
Since July 2011, I was engaged in the research of algae cell biology in the Institute of Hydrobiology, Chinese Academy of Sciences. I joined Professor Sabeeha Merchant’s laboratory at UC Berkeley as a visiting scholar during July 2019 to July 2020. I mainly focus on the formation and function of subcellular organelles (such as cilia, ciliary ectosomes, lysosome-related organelles and gas vesicles), and the transformation mechanism of heavy metals by microalgae. This study first optimized a method for purifying lysosome-related organelles (LROs) from two populations of cells. It was proved that the LROs of Chlamydomonas reinhardtii are heterogeneous organelles, which have different morphology and protein composition in response to different environmental conditions. It was further proved that LROs is an important storage site and regulation center for the intracellular phosphorus and metal ions. These results provide a framework for studying the biogenesis of LROs and the mechanisms by which they participate in regulating metal ion metabolism, and provide a new direction for developing microalgae as a material for bioremediation of heavy metal pollution in the environment.
龙欢博士简介
论文：Structural and functional regulation of Chlamydomonas lysosome-related organelles in response to environmental changes
姓名：龙欢
当前职位：中国科学院水生生物研究所，副研究员
教育经历：
2005.09–2011.06
华中农业大学，生物化学与分子生物学专业，理学博士
（其间：2009.09–2010.09 德国弗莱堡大学, 国家公派留学联合培养博士生）
2001.09–2005.06
华中农业大学生物技术专业国家理科基地班，理学学士
（其间：2003.03–2005.06 武汉大学法学院，法学学士<辅修>）
兴趣爱好：阅读、美食
个人简介：2011年7月至今，在中国科学院水生生物研究所从事藻类细胞生物学方向研究工作；其间于2019年7月至2020年7月在美国加州大学伯克利分校Sabeeha Merchant教授实验室做访问学者。主要研究细胞器（纤毛、纤毛囊泡、溶酶体相关细胞器、气囊等）的形成与功能及微藻对重金属的吸收和转化机理。本研究成功分离纯化了两种细胞状态下莱茵衣藻的溶酶体相关细胞器（LROs），证明衣藻LROs是一种异质性细胞器，其响应外界的不同环境具有不同的形态结构和蛋白组成；进一步证明LROs是固存胞内的磷和金属离子并调控其代谢的重要位点。研究结果为进一步研究LROs的形成及其调控金属离子代谢的机制打下基础，为研究微藻作为生物修复环境重金属污染的材料提供了新的方向。
