Haiqi Fu: The Plant Cell First Author

Haiqi Fu, first author of “SALT OVERLY SENSITIVE 1 is inhibited by clade D Protein phosphatase 2C D6 and D7 in Arabidopsis thaliana”

Current Position: Research Assistant

Education: Ph. D. in Biochemistry and Molecular Biology. College of Biological Sciences, China Agriculture University

Non-scientific Interests: Sports

Brief Bio: I was admitted to College of Biological Sciences, China Agricultural University as a graduate student in September 2015, and graduated in June 2022 with a Ph.D. degree. My supervisor was prof. Yan Guo. I majored in Biochemistry and Molecular Biology and my research mainly focused on studying plant salt stress response.

In this study, I identified two phosphatases which inhibited the activity of the Na⁺/H⁺ antiporter SOS1 in non-stress condition, and illustrated that, under salt stress, a calcium sensor SCaBP8 released the inhibition of SOS1 by repressing the PP2C activity and regulating their subcellular localization. Our results suggest that both the phosphorylation and dephosphorylation are critical for the regulation of the SOS1 activity, and a salt-induced calcium signal functions in both the activation of SOS2 kinase and deactivation of PP2Cs.

姓    名: 付海奇

目前职位: 科研助理

教育背景: 中国农业大学 博士学位

兴趣爱好: 体育运动

个人简介: 本人于2015年9月考入中国农业大学生物学院攻读研究生, 于2022年6月取得博士学位。研究生期间师从郭岩教授, 专业为生物化学与分子生物学，研究方向为植物抵抗盐胁迫的机制探索。

在本研究中, 我们鉴定出两个磷酸酶, 可以在非胁迫环境下抑制钠氢离子转运体SOS1活性的, 并阐明在盐胁迫下钙结合蛋白SCaBP8通过调节这两个磷酸酶的活性以及亚细胞定位解除了磷酸酶PP2C对于SOS1的抑制。我们的结果说明磷酸化与去磷酸化修饰对于SOS信号通路的活性调节同样重要, 同时盐胁迫下的钙信号在激活激酶SOS2与抑制磷酸酶PP2C的两个过程中均发挥着重要作用。