Recent Blog Posts by Category

Review: Using CRISPR/Cas in three dimensions: towards synthetic plant genomes, transcriptomes and epigenomes

Puchta reviews the different ways that CRISPR/Cas9 can be used in synthetic biolgy, beyond the common gene-editing function. For example, the Cas9 protein can be fused to other proteins that activate or repress transcription, and targeted to different promoters using guide RNAs. He further explores the…