Xiaoxiao Li: The Plant Cell First Author

Xiaoxiao Li, co-first author of “Ectopic expression of BOTRYTIS SUSCEPTIBLE1 reveals its function as a positive regulator of wound-induced cell death and plant susceptibility to Botrytis”

Current Position: Ph.D. candidate at Zhejiang University

Education: M.S., Zhejiang A&F University

Non-scientific Interests: Travelling and history

Brief bio: I started my post-graduate studies at College of Forestry and Biotechnology in Zhejiang A&F University since 2018 and afterwards had the honor to join Prof.  Fuqiang Cui’s research group to pursue a master’s degree in biochemistry and molecular biology. During this stage, I focused on research stress responses, immunity, and development. With an interest in plant immunity, I continued my doctoral studies at Prof. Tao’s lab in 2022.In this year, I was a co-first author of an article published in The Plant Cell that BOS1 positively regulates cell death. In this work, we discovered that bos1-1 is a gain-of-function mutant and that BOS1 function in regulation of fertility and Botrytis response can both be understood as misregulated cell death. In the future, I will intend to keep research on the scientific mysteries surrounding the plant immunity.

李潇潇

发表论文：Ectopic expression of BOTRYTIS SUSCEPTIBLE1 reveals its function as a positive regulator of wound-induced cell death and plant susceptibility to Botrytis

目前职位：浙江大学在读博士

教育经历：浙江农林大学硕士

兴趣爱好：旅游，历史

个人简介：我于2018年进入浙江农林大学亚热带森林培育国家重点实验室崔富强副教授课题组进行损伤诱导的细胞程序性死亡以及灰霉菌响应方面的分子机制研究。bos1-1是一个T-DNA插入在5’ UTR处的突变体，之前的研究一直认为bos1-1突变体损伤诱导的细胞扩散性死亡表型以及灰霉菌敏感表型是由于BOS1基因的缺失造成的，由于缺少合适的突变体，对于bos1-1突变体中BOS1基因表达量过高这一现象并没有合理的解释。在此研究中，我们通过对bos1-1突变体基因组的重测序以及利用CRISPR/Cas9技术构建BOS1外显子突变体，发现了bos1-1是一个功能获得性突变体。此外，通过多个过表达系植株证明了BOS1以剂量依赖性方式参与细胞死亡以及灰霉菌敏感性的调控。